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Patient Guide

5 Clinical Trial Myths That Could Be Holding You Back

December 18, 2025 6 min read

Clinical trials are often misunderstood, and these misconceptions can prevent patients from accessing treatments that could help them. Let's address the most common myths.

Myth 1: Clinical Trials Are Only for Patients Who Have No Other Options

Reality: Many trials are designed for patients at all stages of treatment. Some trials test new first-line treatments, while others explore combinations with existing therapies. You don't have to exhaust all options before considering a trial.

Myth 2: I Might Get a Placebo Instead of Real Treatment

Reality: In cancer trials, placebos are rarely used alone. When placebos are part of a study, they're typically combined with standard treatment—meaning everyone receives at least the current standard of care. Many trials compare two active treatments with no placebo at all.

Myth 3: Clinical Trials Are Experimental and Dangerous

Reality: Before any treatment reaches a clinical trial in humans, it goes through years of laboratory and animal testing. Trials are also carefully monitored by independent safety boards. While there are risks (as with any medical treatment), these are explained in detail during the informed consent process.

Myth 4: My Doctor Would Have Mentioned Trials If They Were Right for Me

Reality: Doctors are busy and may not always be aware of every trial available. With thousands of active trials and constantly changing eligibility criteria, it's worth doing your own research and bringing options to your oncologist.

Myth 5: Clinical Trials Are Too Far Away or Too Expensive

Reality: Many trials cover some or all treatment costs, and some even provide travel assistance. With trials running at hundreds of locations nationwide, there may be options closer than you think.

Take Action

Don't let myths hold you back. Use ClinicalMatch.ai to find trials matching your specific mutation profile, then discuss the options with your oncologist.

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